Ralf Werner Selected Research

Androgen-Insensitivity Syndrome (Testicular Feminization)

1/2022	Metabolic effects of estradiol versus testosterone in complete androgen insensitivity syndrome.
1/2021	In vitro functional characterization of androgen receptor gene mutations at arginine p.856 of the ligand-binding-domain associated with androgen insensitivity syndrome.
12/2018	Epigenetic Repression of Androgen Receptor Transcription in Mutation-Negative Androgen Insensitivity Syndrome (AIS Type II).
10/2018	Oestrogen versus androgen in hormone-replacement therapy for complete androgen insensitivity syndrome: a multicentre, randomised, double-dummy, double-blind crossover trial.
1/2017	Functional Impact of Novel Androgen Receptor Mutations on the Clinical Manifestation of Androgen Insensitivity Syndrome.
1/2016	A Recurrent Germline Mutation in the 5'UTR of the Androgen Receptor Causes Complete Androgen Insensitivity by Activating Aberrant uORF Translation.
1/2015	Characteristic features of reproductive hormone profiles in late adolescent and adult females with complete androgen insensitivity syndrome.
1/2014	Preserved fertility in a patient with gynecomastia associated with the p.Pro695Ser mutation in the androgen receptor.
1/2014	Androgen action.
1/2013	Minor hypospadias: the "tip of the iceberg" of the partial androgen insensitivity syndrome.

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Ralf Werner Research Topics

Disease

16	Androgen-Insensitivity Syndrome (Testicular Feminization) 01/2022 - 09/2006
6	46,XY Disorder of Sex Development (Male Pseudohermaphroditism) 01/2019 - 04/2010
5	Pseudohypoparathyroidism 12/2016 - 06/2011
3	Disorders of Sex Development (Intersexuality) 02/2022 - 06/2009
3	Virilism (Virilization) 02/2022 - 09/2006
1	Hypospadias 01/2022
1	Cryptorchidism (Undescended Testes) 01/2022
1	Rickets (Rachitis) 11/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2020
1	Atherosclerosis 01/2020
1	Mixed Gonadal Dysgenesis 01/2019
1	Endocrine System Diseases (Endocrine Diseases) 12/2018
1	De Lange Syndrome (Cornelia De Lange Syndrome) 11/2018
1	Amenorrhea 01/2017
1	Uniparental Disomy 04/2015
1	Pseudopseudohypoparathyroidism 03/2015
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2015
1	Gonadal Dysgenesis (Gonadal Agenesis) 01/2015
1	Male Infertility (Male Sterility) 01/2014
1	Gynecomastia 01/2014
1	Carcinoma (Carcinomatosis) 11/2006

Drug/Important Bio-Agent (IBA)

12	AndrogensIBA 12/2018 - 09/2006
11	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 09/2006
6	Testosterone (Sustanon)FDA Link 02/2022 - 01/2017
3	SteroidsIBA 01/2019 - 01/2015
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 06/2011
3	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 01/2013
3	Hormones (Hormone)IBA 01/2015 - 01/2014
2	GonadotropinsIBA 01/2022 - 01/2015
2	Apolipoproteins D (Apo D)IBA 10/2019 - 06/2009
2	Parathyroid Hormone (Parathormone)IBA 12/2016 - 03/2015
2	GTP-Binding Proteins (G-Protein)IBA 08/2014 - 06/2011
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 08/2011 - 06/2011
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2022
1	Arginine (L-Arginine)FDA Link 01/2021
1	LigandsIBA 01/2021
1	Phosphates (Orthophosphate)IBA 11/2020
1	Apolipoproteins E (ApoE)IBA 01/2020
1	LipidsIBA 01/2020
1	Messenger RNA (mRNA)IBA 10/2019
1	Prostaglandins DIBA 01/2019
1	CohesinsIBA 11/2018
1	Parathyroid Hormone-Related ProteinIBA 12/2016
1	5' Untranslated Regions (5' UTR)IBA 01/2016
1	5-phenylpent-4-enyl-1-hydroperoxideIBA 03/2015
1	inhibin BIBA 01/2015
1	Biomarkers (Surrogate Marker)IBA 06/2009
1	polyglutamineIBA 09/2006

Therapy/Procedure

1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 10/2018
1	Castration 10/2018
1	Therapeutics 04/2010